Dementia pugilistica

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Synonyms: Boxer's dementia | Chronic traumatic encephalopathy | Punch-drunk syndrome

A rare neurologic disease characterized by progressive neurodegeneration secondary to repetitive mild traumatic brain injuries. The clinical picture is highly variable and includes behavioral or psychiatric symptoms (such as aggression depression delusions and suicidality) cognitive impairment (including diminished attention memory deficits executive functioning deficits and dementia) and motor deficits (including parkinsonism ataxia and dysarthria). Neuropathological hallmark is the accumulation of phosphorylated tau-protein in sulci and perivascular regions.

Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview. Reference: Access aggregated data from Orphanet at Orphadata. Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version June 2024

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Dementia pugilistica?

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