Immunodeficiency due to MASP-2 deficiency
Immunodeficiency due to MASP-2 deficiency is a rare genetic immunodeficiency due to a complement cascade protein anomaly characterized by low serum levels of MASP-2 and a variable susceptibility to bacterial infections (e.g. pulmonary tuberculosis pneumococcal pneumonia skin abscesses and sepsis) and autoimmune diseases (e.g. inflammatory lung disease cystic fibrosis systemic lupus erythematosus). In many cases it remains asymptomatic.
Data from Orphanet are used to provide information on a disease's name, synonym(s), and overview.
Orphadata: Free access data from Orphanet. © INSERM 1999. Available on http://www.orphadata.org. Data version March 2024
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Immunodeficiency due to MASP-2 deficiency?
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